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Personal Exposure to Submicrometer Particles and Heart Rate Variab...

By: Kai Jen Chuang

Government Reference Publication

Excerpt: We conducted a study on two panels of human subjects?9 young adults and 10 elderly patients with lung function impairments?to evaluate whether submicrometer particulate air pollution was associated with heart rate variability (HRV). We measured these subjects electrocardiography and personal exposure to number concentrations of submicrometer particles with a size range of 0.02?1 micrometer (NC0.02?1) continuously during daytime periods. We used linear mixed-effe...

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Effects of Particle Size Fractions on Reducing Heart Rate Variabil...

By: Kai Jen Chuang

Government Reference Publication

Excerpt: It is still unknown whether the associations between particulate matter (PM) and heart rate variability (HRV) differ by particle sizes with aerodynamic diameters between 0.3 micrometer and 1.0 micrometer (PM0.3?1.0), between 1.0 micrometer and 2.5 micrometer (PM1.0?2.5), and between 2.5 micrometer and 10 micrometer (PM2.5?10). We measured electrocardiographics and PM exposures in 10 patients with coronary heart disease and 16 patients with either prehypertension...

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Distribution of Methyl Sulfone Metabolites of Polychlorinated Biph...

By: Shaogang Chu

Government Reference Publication

Excerpt: We determined methylsulfonyl metabolites of chlorinated biphenyls (MeSO2-CBs) and 1,1-bis(4- chlorophenyl)-2,2-dichloroethene (p,p-DDE) in human adipose, liver, brain, and lung tissues obtained from 11 Belgian individuals (9?62 years of age). The total concentration of MeSO2-CBs (lipid weight basis) decreased in the following order: liver (mean, 9.30 ng/g; range, 1.68?27.03 ng/g lipid) > lung [mean, 2.72 ng/g; range, not detected (ND) to 11.54 ng/g lipid] > adip...

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Review of Experimental Carcinogenesis by Compounds Related to Viny...

By: Kenneth C. Chu

Government Reference Publication

Introduction: related compounds have been increasing. This paper Since the carcinogenicity of vinyl chloride (VC) will attempt to review the experimental carcinogewas demonstrated in experimental (1) and epid- nicity data on a number of these compounds, while emiologic studies (Z), data on the potential carcino- another paper (8) will discuss the epidemiologic genicity of vinyl chloride structural analogs and results.

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Negative Ions of Polyatomic Molecules

By: L. G. Christophorou

Government Reference Publication

Excerpt: Basic -Electron Attachment Processes metastable atoms, Rydherg states) will not be discussed. The basic processes to he considered, then, can be classified as electron attachment to ground state molecules, to hot molecules, or to This paper deals with negative ions formed in electronically excited molecules. electron-molecule collisions at low energies (515 Electron attachment to ground state moleeV). Negative ions produced at higher energies cules predominantly...

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Human Liver Tumors in Relation to Steroidal Usage

By: W. M. Christopherson

Government Reference Publication

Excerpt: Since 1973, an apparent association between benign liver tumors and steroid administration has been widely publicized. Although Baum (1) first drew widespread attention to the association with a report describing seven cases of benign hepatomas, other authors had previously reported cases with steroid association (2,3)B. y 1977 over 500 r e ports associating liver tumors with steroid use had appeared in the literature, most by case reports and small series (4). ...

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The Niehs and the National Toxicology Program : An Integrated Scie...

By: Christopher J. Portier, Ph. D.

Government Reference Publication

Excerpt: The National Toxicology Program (NTP) is an interagency program whose mission is to coordinate, conduct, and communicate toxicological research findings across the U.S. government. The NTP is administratively housed at the NIEHS, and David Schwartz serves as the director of both the NTP and the NIEHS. The NTP and the NIEHS share an integrated vision that serves to enhance the productivity of each program by promoting extensive collaboration across the broad spec...

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Use of Haploid Plants as Bioassays for - Mutagens

By: M. L. Christianson

Government Reference Publication

Introduction: Mutagenic agents typically effect several mutational processes. In mouse erythoblasts, for example, a known bacterial frame-shift mutagen produces chromosome fragments (I) . Most bioassays for mutagenic activity by use of higher plants simply measure the total number of mutations; the partitioning of this quantitative measurement into categories-sectors due to deletion, due to point mutation, due to gene conversion, and so on-is not, and usually could not, ...

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Environmental Organochlorines and Semen Quality : Results of a Pil...

By: David C. Christiani

Government Reference Publication

Excerpt: Currently there is scientific and public concern about whether exposure to ambient levels of so-called endocrine disruptors, such as p,p-DDE [1,1-dichloro-2,2-bis(p-chlorophenyl) ethylene], a metabolite of DDT [1,1,1-dichloro 2,2-bis(p-chlorophenyl)- 1,1,1-trichloroethane], and polychlorinated biphenyls (PCBs), alter semen quality (1,2). This concern stems from studies showing that PCBs and p,p-DDE are found in a large proportion of the general population (3?5),...

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Case Report : Occupationally Related Recurrent Varicella (Chickenp...

By: David C. Christiani

Government Reference Publication

Excerpt: Commonly accepted outcomes of varicella-zoster virus (VZV) infections include chickenpox (primary) and shingles (recurrence or latency), as well lifetime immunity against chickenpox. We report the case of a registered nurse who worked in a neurologic surgery ward in a general hospital in Taipei, Taiwan. While working there for approximately 1 year, she developed recurrent chickenpox after caring for a paraparesis patient, who had herpes zoster during hospitaliza...

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Association of Expired Nitric Oxide with Occupational Particulate ...

By: David C. Christiani

Government Reference Publication

Excerpt: Particulate air pollution has been associated with adverse respiratory health effects. This study assessed the utility of expired nitric oxide to detect acute airway responses to metal-containing fine particulates. Using a repeated-measures study design, we investigated the association between the fractional concentration of expired nitric oxide (FENO) and exposure to particulate matter with an aerodynamic mass median diameter of <= 2.5 micrometer (PM2.5) in boi...

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September 11 More Effective Collaboration Could Enhance Charitable...

By: General Accounting Office

Government Accountability Integrity Reliability Office Collection

Excerpt: Although it may be difficult to precisely tally the total amount of funds raised in response to the September 11 attacks, 35 of the larger charities have reported raising an estimated $2.7 billion since September 11, 2001. About 70 percent of the money that has been collected by these 35 charities has been reported distributed to survivors or spent on disaster relief since September 11, 2001. Charities used the money they collected to provide direct cash assista...

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September 11 More Effective Collaboration Could Enhance Charitable...

By: General Accounting Office

Government Accountability Integrity Reliability Office Collection

Excerpt: Although it may be difficult to precisely tally the total amount of funds raised in response to the September 11 attacks, 35 of the larger charities have reported raising an estimated $2.7 billion since September 11, 2001. About 70 percent of the money that has been collected by these 35 charities has been reported distributed to survivors or spent on disaster relief since September 11, 2001. Charities used the money they collected to provide direct cash assista...

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September 11 Interim Report on the Response of Charities

By: General Accounting Office

Government Accountability Integrity Reliability Office Collection

Excerpt: Appendix I Congressional Briefing Slides 6 Appendix II Additional Fund Information 35 Appendix III Information on Federal Victim Compensation Fund 37 Contents...

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September 11 Interim Report on the Response of Charities

By: General Accounting Office

Government Accountability Integrity Reliability Office Collection

Excerpt: Appendix I Congressional Briefing Slides 6 -- Appendix II Additional Fund Information 35 -- Appendix III Information on Federal Victim Compensation Fund 37 -- Contents...

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Senior Executive Service Enhanced Agency Efforts Needed to Improve...

By: General Accounting Office

Government Accountability Integrity Reliability Office Collection

Excerpt: More than half of the 6 00 career SES members employed on October 1, 2000, will have left service by October 1, 2007. Using recent SES appointment trends, the only significant changes in diversity would be an increase in the number of white women and an essentially equal decrease in white men. The percentage of GS-15s and GS-14s projected to leave would be lower (47 percent and 34 percent, respectively), and we project that the number of minorities still in the ...

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Senior Executive Service Enhanced Agency Efforts Needed to Improve...

By: General Accounting Office

Government Accountability Integrity Reliability Office Collection

Excerpt: More than half of the 6 00 career SES members employed on October 1, 2000, will have left service by October 1, 2007. Using current SES appointment trends, the only significant changes in diversity will be an increase in the number of white women and an essentially equal decrease in white men.

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Selection of Antiretroviral Medications Provided under U.S. Emerge...

By: General Accounting Office

Government Accountability Integrity Reliability Office Collection

Excerpt: The Emergency Plan provides a smaller selection of recommended first-line ARVs than other major HIV/AIDS treatment initiatives in developing countries. The plan?s selection includes six original ARV products-the only ARVs that have met the plan?s quality assurance requirement-and does not include some FDCs that are preferred by most of the focus countries because they can simplify treatment. In contrast, the other initiatives provide a selection that in addition...

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Selection and Implementation of the Office of Management and Budge...

By: General Accounting Office

Government Accountability Integrity Reliability Office Collection

Excerpt: OMB?s e-government task force developed abbreviated (?mini?) business cases on which to base its selection of initiatives. GAO compared the content of these mini business cases with best practices for the content of e-government business cases. Based on this comparison, all the business cases contained at least some of the key information needed, but many elements were missing (see figure). In particular, fewer than half addressed collaboration and customer focu...

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Selected Nations Reports on Greenhouse Gas Emissions Varied in The...

By: General Accounting Office

Government Accountability Integrity Reliability Office Collection

Excerpt: In their most recent reviews, expert teams found that the United Kingdom?s 2000 and 2002 reports on greenhouse gas emissions and the United States?s 2000 report were largely complete, although the teams noted minor findings, such as the lack of information on quality assurance methods, which the nations were encouraged, but not required, to include in their submissions. In contrast, they found that Germany?s 2001 and Japan?s 2000 reports lacked critical elements...

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