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Plos One : Sickness Absence Due to Specific Mental Diagnoses and A...

By: Marianna Mazza

Description : Knowledge about the prognosis of patients sickness absent with specific mental diagnoses is of crucial clinical importance in health care. Sickness absence due to specific mental diagnoses may here be used as a risk indictor for subsequent mortality

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Plos One : Contributory Role of Five Common Polymorphisms of Rage ...

By: Giuseppe Novelli

Description : Our findings demonstrated a potential interactive contribution of RAGE and APE1 genes to the pathogenesis of lung cancer among Han Chinese. Further studies are warranted to confirm or refute these findings.

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Plos One : Endogenous Opioids in Wound-site Neutrophils of Sternot...

By: Colin Combs

Description : This approach provided a unique opportunity to study the cross-talk between inflammation and opioid peptides in PMN at a sternotomy wound-site. Wound-site PMN exhibited induction of END and ENK. In addition, sternal wound fluid significantly induced END expression in PMN. Taken together, these data constitute first clinical evidence that human wound-site PMNs are direct contributors of opioids at the sternal wound-site.

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Plos One : Toll-like Receptor 2 and Toll-like Receptor 4-dependent...

By: Robert Lafrenie

Description : Various natural polysaccharides are capable of activating the immune system and therefore can be employed as biological response modifiers in anti-tumor therapy. We previously found a homogenous polysaccharide from the mycelium of marine fungus Phoma herbarum YS4108, named YCP, exhibiting strong in vivo antitumor ability via enhancement of the host immune responses. To further elucidate the role of YCP as a biological response modifier, the immunomoduating ...

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Plos One : Receiving Palliative Treatment Moderates the Effect of ...

By: Tak Wing Lam

Description : Existential distress in terms of demoralization is a relevant problem within the spectrum of cancer-related distress. It is associated with a complex interaction of demographic and medical patient characteristics: existential challenges related to palliative treatment may exacerbate the impact of age- and gender-related vulnerability factors on demoralization. Psychosocial interventions should acknowledge this interaction in order to address the individual ...

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