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Environmental Genome Project

By Wakefield, Julie

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Book Id: WPLBN0000017663
Format Type: PDF eBook
File Size: 7.3 MB
Reproduction Date: 2005

Title: Environmental Genome Project  
Author: Wakefield, Julie
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Wakefield, J. (n.d.). Environmental Genome Project. Retrieved from

Government Reference Publication

Excerpt: As the Environmental Genome Project (EGP) marks its fifth anniversary in 2003, there is some cause for celebration. Although it is premature to expect the project to have any impact on public health and policy yet, the EGPs science and technology are advancing in step with its original goals of understanding the complex interrelationship between environmental exposure, genetic susceptibility, and human disease. The NIEHS began the EGP in late 1997. The EGP is a multicomponent project comprising extramural and intramural research in several key areas. In addition to enhancing understanding of human genetic susceptibility to environmental exposure?how individuals differ in susceptibility to environmental agents, and how such susceptibilities change over time?other topics of interest are dose response, identification of sensitive subpopulations, and selection of appropriate test systems for human responses. EGP research is also looking at selected genes in different individuals to learn the extent and location of variations in a single DNA pair, also called single nucleotide polymorphisms, or SNPs. SNP variations are thought to be central to why people respond differently to various drugs or environmental toxicants.


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