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Environmental Organochlorines and Semen Quality : Results of a Pilot Study

By Christiani, David C.

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Book Id: WPLBN0000000377
Format Type: PDF eBook
File Size: 0.6 MB
Reproduction Date: 2005

Title: Environmental Organochlorines and Semen Quality : Results of a Pilot Study  
Author: Christiani, David C.
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Christiani, D. C. (n.d.). Environmental Organochlorines and Semen Quality : Results of a Pilot Study. Retrieved from

Government Reference Publication

Excerpt: Currently there is scientific and public concern about whether exposure to ambient levels of so-called endocrine disruptors, such as p,p-DDE [1,1-dichloro-2,2-bis(p-chlorophenyl) ethylene], a metabolite of DDT [1,1,1-dichloro 2,2-bis(p-chlorophenyl)- 1,1,1-trichloroethane], and polychlorinated biphenyls (PCBs), alter semen quality (1,2). This concern stems from studies showing that PCBs and p,p-DDE are found in a large proportion of the general population (3?5), as well as animal and human studies suggesting possible associations of exposure to PCBs and p,p-DDE with semen abnormalities and altered testis function (6?8). The U.S. Environmental Protection Agency (EPA) National Human Adipose Tissue Survey estimated that > 95% of the U.S. population had detectable levels of PCBs (9). It is estimated that > 99% of individuals have detectable blood levels of p,p-DDE (4).


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