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Effect of Size of Man-Made and Natural Mineral Fibers on Chemiluminescent Response in Human Monocyte-Derived Macrophages

By Ohyama, Masayuki

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Book Id: WPLBN0000169438
Format Type: PDF eBook
File Size: 0.6 MB
Reproduction Date: 2005

Title: Effect of Size of Man-Made and Natural Mineral Fibers on Chemiluminescent Response in Human Monocyte-Derived Macrophages  
Author: Ohyama, Masayuki
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Historic
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)

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Ohyama, M. (n.d.). Effect of Size of Man-Made and Natural Mineral Fibers on Chemiluminescent Response in Human Monocyte-Derived Macrophages. Retrieved from http://netlibrary.net/


Description
Government Reference Publication

Excerpt
Excerpt: Exposure to amphibole asbestos is associated with the development of mesotheliomas, lung cancers, and fibrotic lung diseases (1,2). Therefore, man-made and natural mineral fibers often have been substituted for asbestos. Although numerous inhalation studies demonstrated no significant increase in tumor incidence in animals exposed to such substitutes (3?5), several mineral fibers (refractory ceramic fiber and fiber glass) were carcinogenic in rodent chronic inhalation studies (6,7). Morover, in animal intraperitoneal studies, the fiber length of asbestos and other mineral fibers has been found to be one of the major descriptors of tumorigenicity (8?10). Therefore, we considered that the extensive knowledge on asbestos may apply to other mineral fibers tumorigenicity.

 

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