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A Method for in Vitro Culture of Rat Zymbal Gland : Use in Mechanistic Studies of Benzene Carcinogenesis in Combination with 32 Post Labeling

By Reddy, M. Vijayaraj

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Book Id: WPLBN0000192923
Format Type: PDF eBook
File Size: 1.1 MB
Reproduction Date: 2005

Title: A Method for in Vitro Culture of Rat Zymbal Gland : Use in Mechanistic Studies of Benzene Carcinogenesis in Combination with 32 Post Labeling  
Author: Reddy, M. Vijayaraj
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Historic
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Publisher: United Nations- Office for Disarmament Affairs (Unoda)

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Reddy, M. V. (n.d.). A Method for in Vitro Culture of Rat Zymbal Gland : Use in Mechanistic Studies of Benzene Carcinogenesis in Combination with 32 Post Labeling. Retrieved from http://netlibrary.net/


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Government Reference Publication

Excerpt
Excerpt: Rat Zymbal glands, located at the base of the external auditory canal, have a distinctive pink-yellow color, weigh about 7 to 8 mg, and have a diameter of 3 to 5 mm. These glands, also present in other rodents and insectivores, but not in humans, have a typical sebaceous morphology, which is characterized by rounded sacs of plump, fatcontaining cells (1). These cells subsequently break down, releasing fat droplets into the external ear canal (1). Maltoni et al. (2) and the National Toxicology Program (3) have reported a dm-dependent formation of solid tumors in Zymbal glands of rats following administration of repeated high doses of benzene. The mechanism by which.

 

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