World Library  

Add to Book Shelf
Flag as Inappropriate
Email this Book

Advances in Protein Chemistry

By Ashraf, Chulam, Dr.

Click here to view

Book Id: WPLBN0003468664
Format Type: PDF (eBook)
File Size: 14.12 MB.
Reproduction Date: 1/1/2014

Title: Advances in Protein Chemistry  
Author: Ashraf, Chulam, Dr.
Language: English
Subject: Non Fiction, Medicine, Protein chemistry
Collections: Medicine, Biology, Authors Community, Chemistry, Pathology, Literature
Publication Date:
Publisher: OMICS Group
Member Page: OMICS eBooks

The free radical-mediated damage to proteins results in the modification of amino acid residues, cross-linking of side chains and fragmentation. L-tyrosine and protein bound tyrosine are prone to attack by various mediators and reactive nitrogen intermediates to form 3-nitrotyrosine (3-NT). 3-NT formation is also catalyzed by a class of peroxidases utilizing nitrite and hydrogen peroxide as substrates. Evidence supports the formation of 3-NT in vivo in diverse pathologic conditions and 3-NT is thought to be a relatively specific marker of oxidative damage. The formation of nitrotyrosine represents a specific peroxynitrite-mediated protein modification; thus, detection of nitrotyrosine in proteins is considered as a biomarker for endogenous peroxynitrite activity. Formation of tyrosine nitrated proteins is considered to be a post-translational modification with important pathophysiological consequences and is one of the markers of nitrosative stress that have been reported in neurodegeneration, inflammatory and other pathological conditions.


Click To View

Additional Books

  • Ruling Chiefs of Hawaii (by )
  • Hawaii Place Names (by )
  • Ko Pele Hiki 'Ana Mai I Hawai'I (by )
  • The Loudest Voice in the World (by )
  • Easy : Dashuria nuk është gjithmonë e le... (by )
  • Aia He Kaheka (by )
  • A Tale of Two Cities (by )
  • Glorious Ukrainian Bride Wants YOU!: Sto... (by )
  • 666 The Mark of the Beast : REV 13.16 (by )
  • Unidentified Aerial Phenomena in the UK ... Volume No. 55/2/00 (by )
  • 2017 Letter to My Parents Contest Los An... (by )
  • He Pule Hoolaa Alii (A Prayer Consecrati... (by )
Scroll Left
Scroll Right


Copyright © World Library Foundation. All rights reserved. eBooks from World Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.