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Plos Biology : Motifs in Brain Networks, Volume 2

By Friston, Karl J.

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Book Id: WPLBN0003922989
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos Biology : Motifs in Brain Networks, Volume 2  
Author: Friston, Karl J.
Volume: Volume 2
Language: English
Subject: Journals, Science, Biology
Collections: Periodicals: Journal and Magazine Collection (Contemporary), PLoS Biology
Publication Date:
Publisher: Plos


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Friston, K. J. (n.d.). Plos Biology : Motifs in Brain Networks, Volume 2. Retrieved from

Description : Complex brains have evolved a highly efficient network architecture whose structural connectivity is capable of generating a large repertoire of functional states. We detect characteristic network building blocks (structural and functional motifs) in neuroanatomical data sets and identify a small set of structural motifs that occur in significantly increased numbers. Our analysis suggests the hypothesis that brain networks maximize both the number and the diversity of functional motifs, while the repertoire of structural motifs remains small. Using functional motif number as a cost function in an optimization algorithm, we obtain network topologies that resemble real brain networks across a broad spectrum of structural measures, including small-world attributes. These results are consistent with the hypothesis that highly evolved neural architectures are organized to maximize functional repertoires and to support highly efficient integration of information.


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