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Plos Neglected Tropical Diseases : Characterization of the Entamoeba Histolytica Ornithine Decarboxylase-like Enzyme, Volume 2

By Lohia, Anuradha

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Book Id: WPLBN0003923735
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos Neglected Tropical Diseases : Characterization of the Entamoeba Histolytica Ornithine Decarboxylase-like Enzyme, Volume 2  
Author: Lohia, Anuradha
Volume: Volume 2
Language: English
Subject: Journels, Science, Neglected Tropical Diseases
Collections: Periodicals: Journal and Magazine Collection (Contemporary), PLoS Neglected Tropical Diseases
Historic
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Publisher: Plos

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Lohia, A. (n.d.). Plos Neglected Tropical Diseases : Characterization of the Entamoeba Histolytica Ornithine Decarboxylase-like Enzyme, Volume 2. Retrieved from http://netlibrary.net/


Description
Description : To our knowledge this is the first report on the molecular characterization of putative ODC-like sequence from E. histolytica. Computer modeling revealed that three of the critical residues required for binding of DFMO to the ODC enzyme are substituted in E. histolytica, resulting in the likely loss of interactions between the enzyme and DFMO.

 

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