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Plos Neglected Tropical Diseases : Profile of Central and Effector Memory T Cells in the Progression of Chronic Human Chagas Disease, Volume 3

By Rodriguez, Ana

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Book Id: WPLBN0003925187
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos Neglected Tropical Diseases : Profile of Central and Effector Memory T Cells in the Progression of Chronic Human Chagas Disease, Volume 3  
Author: Rodriguez, Ana
Volume: Volume 3
Language: English
Subject: Journels, Science, Neglected Tropical Diseases
Collections: Periodicals: Journal and Magazine Collection (Contemporary), PLoS Neglected Tropical Diseases
Historic
Publication Date:
Publisher: Plos

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Rodriguez, A. (n.d.). Plos Neglected Tropical Diseases : Profile of Central and Effector Memory T Cells in the Progression of Chronic Human Chagas Disease, Volume 3. Retrieved from http://netlibrary.net/


Description
Description : Based on a correlation between the frequency of IFN-c producing CD8+ T cells in the T cell memory compartment and the chronic chagasic myocarditis, we propose that memory T cells can be involved in the induction of the development of the severe clinical forms of the Chagas disease by mechanisms modulated by IFN-c. Furthermore, we showed that individuals from IND group presented more TCM CD4+ T cells, which may induce a regulatory mechanism to protect the host against the exacerbated inflammatory response elicited by the infection.

 

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