World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos One : Automatic Sampling and Analysis of Organics and Biomolecules by Capillary Action-supported Contactless Atmospheric Pressure Ionization Mass Spectrometry, Volume 8

By Athersuch, Toby, James.

Click here to view

Book Id: WPLBN0003944406
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos One : Automatic Sampling and Analysis of Organics and Biomolecules by Capillary Action-supported Contactless Atmospheric Pressure Ionization Mass Spectrometry, Volume 8  
Author: Athersuch, Toby, James.
Volume: Volume 8
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Athersuch, T. J. (n.d.). Plos One : Automatic Sampling and Analysis of Organics and Biomolecules by Capillary Action-supported Contactless Atmospheric Pressure Ionization Mass Spectrometry, Volume 8. Retrieved from http://netlibrary.net/


Description
Description : Contactless atmospheric pressure ionization (C-API) method has been recently developed for mass spectrometric analysis. A tapered capillary is used as both the sampling tube and spray emitter in C-API. No electric contact is required on the capillary tip during C-API mass spectrometric analysis. The simple design of the ionization method enables the automation of the C-API sampling system. In this study, we propose an automatic C-API sampling system consisting of a capillary (,1 cm), an aluminium sample holder, and a movable XY stage for the mass spectrometric analysis of organics and biomolecules. The aluminium sample holder is controlled by the movable XY stage. The outlet of the C-API capillary is placed in front of the orifice of a mass spectrometer, whereas the sample well on the sample holder is moved underneath the capillary inlet. The sample droplet on the well can be readily infused into the C-API capillary through capillary action. When the sample solution reaches the capillary outlet, the sample spray is readily formed in the proximity of the mass spectrometer applied with a high electric field. The gas phase ions generated from the spray can be readily monitored by the mass spectrometer. We demonstrate that six samples can be analyzed in sequence within 3.5 min using this automatic C-API MS setup. Furthermore, the well containing the rinsing solvent is alternately arranged between the sample wells. Therefore, the C-API capillary could be readily flushed between runs. No carryover problems are observed during the analyses. The sample volume required for the C-API MS analysis is minimal, with less than 1 nL of the sample solution being sufficient for analysis. The feasibility of using this setup for quantitative analysis is also demonstrated.

 

Click To View

Additional Books


  • Plos One : One-step Chromatographic Puri... (by )
  • Plos One : a Novel Micro-linear Vector f... (by )
  • Plos One : Subcutaneous Interferon Β-1A ... (by )
  • Plos One : Comparison of Treatment Outco... (by )
  • Plos One : Veins Improve Fracture Toughn... (by )
  • Plos One : Whole Brain Approaches for Id... (by )
  • Plos One : Impact of Aai-1 Expressed in ... (by )
  • Plos One : Isobaric Tagging-based Quanti... (by )
  • Plos One : Endolymphatic Na+ and K+ Conc... (by )
  • Plos One : Small-scale Habitat Structure... (by )
  • Plos One : Construction of Core Collecti... (by )
  • Plos One : Cool and Hot Executive Functi... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from World Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.