World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos One : Mirandola ; Extracellular Circulating Micrornas Database, Volume 7

By Jeang, K.T.

Click here to view

Book Id: WPLBN0003956908
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos One : Mirandola ; Extracellular Circulating Micrornas Database, Volume 7  
Author: Jeang, K.T.
Volume: Volume 7
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Jeang, K. (n.d.). Plos One : Mirandola ; Extracellular Circulating Micrornas Database, Volume 7. Retrieved from http://netlibrary.net/


Description
Description : MicroRNAs are small noncoding RNAs that play an important role in the regulation of various biological processes through their interaction with cellular messenger RNAs. They are frequently dysregulated in cancer and have shown great potential as tissue-based markers for cancer classification and prognostication. microRNAs are also present in extracellular human body fluids such as serum, plasma, saliva, and urine. Most of circulating microRNAs are present in human plasma and serum cofractionate with the Argonaute2 (Ago2) protein. However, circulating microRNAs have been also found in membranebound vesicles such as exosomes. Since microRNAs circulate in the bloodstream in a highly stable, extracellular form, they may be used as blood-based biomarkers for cancer and other diseases. A knowledge base of extracellular circulating miRNAs is a fundamental tool for biomedical research. In this work, we present miRandola, a comprehensive manually curated classification of extracellular circulating miRNAs. miRandola is connected to miRo` , the miRNA knowledge base, allowing users to infer the potential biological functions of circulating miRNAs and their connections with phenotypes. The miRandola database contains 2132 entries, with 581 unique mature miRNAs and 21 types of samples. miRNAs are classified into four categories, based on their extracellular form : miRNA-Ago2 (173 entries), miRNA-exosome (856 entries), miRNA-HDL (20 entries) and miRNA-circulating (1083 entries). miRandola is available online at : http:/atlas.dmi.unict.it/mirandola/index. html.

 

Click To View

Additional Books


  • Plos One : Multi-scale Biomechanical Rem... (by )
  • Plos One : the Composition of Microbiome... (by )
  • Plos One : Non-motor Symptoms in Patient... (by )
  • Plos One : Estrogen Inhibits Renal Cell ... (by )
  • Plos One : Sleep Extension Normalizes Er... (by )
  • Plos One : Lifting the Veil of Morality ... (by )
  • Plos One : Association Between Ugt1A1*28... (by )
  • Plos One : Comparison and Mapping Facili... (by )
  • Plos One : Characterization of a Tumor-a... (by )
  • Plos One : Next-generation Cdna Screenin... (by )
  • Plos One : Colonization of Abandoned Lan... (by )
  • Plos One : Distributional Learning of Ap... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from World Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.