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Plos One : Size Matters ; Concurrency and the Epidemic Potential of Hiv in Small Networks, Volume 7

By Myer, Landon

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Book Id: WPLBN0003960018
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : Size Matters ; Concurrency and the Epidemic Potential of Hiv in Small Networks, Volume 7  
Author: Myer, Landon
Volume: Volume 7
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection
Historic
Publication Date:
Publisher: Plos

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Myer, L. (n.d.). Plos One : Size Matters ; Concurrency and the Epidemic Potential of Hiv in Small Networks, Volume 7. Retrieved from http://netlibrary.net/


Description
Description : Background : Generalized heterosexual epidemics are responsible for the largest share of the global burden of HIV. These occur in populations that do not have high rates of partner acquisition, and research suggests that a pattern of fewer, but concurrent, partnerships may be the mechanism that provides the connectivity necessary for sustained transmission. We examine how network size affects the impact of concurrency on network connectivity. Methodology/Principal Findings : We use a stochastic network model to generate a sample of networks, varying the size of the network and the level of concurrency, and compare the largest components for each scenario to the asymptotic expected values. While the threshold for the growth of a giant component does not change, the transition is more gradual in the smaller networks. As a result, low levels of concurrency generate more connectivity in small networks. Conclusions/Significance : Generalized HIV epidemics are by definition those that spread to a larger fraction of the population, but the mechanism may rely in part on the dynamics of transmission in a set of linked small networks. Examples include rural populations in sub-Saharan Africa and segregated minority populations in the US, where the effective size of the sexual network may well be in the hundreds, rather than thousands. Connectivity emerges at lower levels of concurrency in smaller networks, but these networks can still be disconnected with small changes in behavior. Concurrency remains a strategic target for HIV combination prevention programs in this context.

 

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