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Plos One : Virtual Screening as a Strategy for the Identification of Xenobiotics Disrupting Corticosteroid Action, Volume 7

By Sun, Kang

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Book Id: WPLBN0003962298
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : Virtual Screening as a Strategy for the Identification of Xenobiotics Disrupting Corticosteroid Action, Volume 7  
Author: Sun, Kang
Volume: Volume 7
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
Publication Date:
Publisher: Plos

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Sun, K. (n.d.). Plos One : Virtual Screening as a Strategy for the Identification of Xenobiotics Disrupting Corticosteroid Action, Volume 7. Retrieved from http://netlibrary.net/


Description
Description : Screening of virtual chemical structure libraries can facilitate the identification of xenobiotics inhibiting 11b- HSD2 and/or activating MR. Lasalocid and AB110873 belong to new classes of 11b-HSD2 inhibitors. The silane AB110873 represents to the best of our knowledge the first industrial chemical shown to activate MR. Furthermore, the MR pharmacophore can now be used for future screening purposes.

 

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