World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos One : Modeling Calcium Wave Based on Anomalous Subdiffusion of Calcium Sparks in Cardiac Myocytes, Volume 8

By Komarova, Yulia

Click here to view

Book Id: WPLBN0003963272
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos One : Modeling Calcium Wave Based on Anomalous Subdiffusion of Calcium Sparks in Cardiac Myocytes, Volume 8  
Author: Komarova, Yulia
Volume: Volume 8
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Komarova, Y. (n.d.). Plos One : Modeling Calcium Wave Based on Anomalous Subdiffusion of Calcium Sparks in Cardiac Myocytes, Volume 8. Retrieved from http://netlibrary.net/


Description
Description : Ca2z sparks and Ca2z waves play important roles in calcium release and calcium propagation during the excitationcontraction (EC) coupling process in cardiac myocytes. Although the classical Fick’s law is widely used to model Ca2z sparks and Ca2z waves in cardiac myocytes, it fails to reasonably explain the full-width at half maximum(FWHM) paradox. However, the anomalous subdiffusion model successfully reproduces Ca2z sparks of experimental results. In this paper, in the light of anomalous subdiffusion of Ca2z sparks, we develop a mathematical model of calcium wave in cardiac myocytes by using stochastic Ca2z release of Ca2z release units (CRUs). Our model successfully reproduces calcium waves with physiological parameters. The results reveal how Ca2z concentration waves propagate from an initial firing of one CRU at a corner or in the middle of considered region, answer how large in magnitude of an anomalous Ca2z spark can induce a Ca2z wave. With physiological Ca2z currents (2pA) through CRUs, it is shown that an initial firing of four adjacent CRUs can form a Ca2z wave. Furthermore, the phenomenon of calcium waves collision is also investigated.

 

Click To View

Additional Books


  • Plos One : Generalized Seasonal Autoregr... (by )
  • Plos One : Highly Mutagenic Exocyclic Dn... (by )
  • Plos One : Uv-light Exposure of Insulin ... (by )
  • Plos One : the Rentg Mice ; a Powerful T... (by )
  • Plos One : Reconstruction of White Matte... (by )
  • Plos One : Concurrent Outbreaks of Chole... (by )
  • Plos One : Conflict of Interest in Spine... (by )
  • Plos One : Characterization of Phase Tra... (by )
  • Plos One : Identification of Parasite-ho... (by )
  • Plos One : Rterial Klotho Expression and... (by )
  • Plos One : the Polarization of the G-pro... (by )
  • Plos One : Quantification of Reverse Tra... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from World Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.