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Human Liver Tumors in Relation to Steroidal Usage

By Christopherson, W. M.

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Book Id: WPLBN0000000380
Format Type: PDF eBook
File Size: 1.4 MB
Reproduction Date: 2005

Title: Human Liver Tumors in Relation to Steroidal Usage  
Author: Christopherson, W. M.
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Christopherson, W. M. (n.d.). Human Liver Tumors in Relation to Steroidal Usage. Retrieved from

Government Reference Publication

Excerpt: Since 1973, an apparent association between benign liver tumors and steroid administration has been widely publicized. Although Baum (1) first drew widespread attention to the association with a report describing seven cases of benign hepatomas, other authors had previously reported cases with steroid association (2,3)B. y 1977 over 500 r e ports associating liver tumors with steroid use had appeared in the literature, most by case reports and small series (4). The frequency of case reports has diminished over the past few years, since the association is now common knowledge, yet controversy continues regarding the type of tumors and their relationship to steroids. The infrequency with which these tumors occur has made it difficult for pathologists to develop a first-hand knowledge of the histology of these lesions (5). For this reason, histologic review of a large number of cases with reference to etiologic factors seemed worthwhile. We have had the opportunity to study in detail the histology of over 250 cases of hepatic tumors, most in patients receiving steroids. This presentation reviews the characteristic features of the lesions collected in this series and data regarding the first 201 cases (6).


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